SMA Research Platform

Evidence graph for Spinal Muscular Atrophy

Biology-first target discovery
Christian Fischer / Bryzant Labs
1,145Targets
453Trials
60Drugs
7Datasets
34,514Sources
43,071Claims
46,973Evidence
29,625Hypotheses
data_updateApr 23, 2026· smanewstoday.com

Targeting JNK pathway may offer new treatment approach for SMA

#smanewstoday

Targeting a stress-activated signaling pathway may offer a new way to treat spinal muscular atrophy (SMA), either on its own or in combination with existing therapies. Researchers found that blocking the c-Jun N-terminal kinase (JNK) pathway with medications significantly reduced disease severity and extended survival in a mouse model of severe SMA. Unlike approved SMA […] The post Targeting JNK pathway may offer new treatment approach for SMA appeared first on SMA News Today .

Source: https://smanewstoday.com/news/targeting-jnk-pathway-offer-new-treatment-approach-sma/ (Wed, 22 Apr 2026)

Ingested by the SMA platform's daily smanewstoday.com RSS pipeline. Cross-linked to our knowledge graph via the news auto-scoring cron.

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