Description

GPCR melatonin receptor — melatonin rescues SMA Smn2B/- mouse + C. elegans (O39 Bowerman Budapest 2026).

Linked hypotheses (12)

• Off-target candidate: **risdiplam** → MTNR1A (iPTM=0.927)
  mechanismconf 93%
• risdiplam off-target binding to MTNR1A
  repurposingconf 93%
• Off-target candidate: **pyridostigmine** → MTNR1A (iPTM=0.932)
  mechanismconf 93%
• Off-target candidate: **risdiplam** → MTNR1A (iPTM=0.928)
  mechanismconf 93%
• Off-target candidate: **risdiplam** → MTNR1A (iPTM=0.931)
  mechanismconf 93%
• Off-target candidate: **riluzole** → MTNR1A (iPTM=0.891)
  mechanismconf 89%
• riluzole off-target binding to MTNR1A
  repurposingconf 89%
• Off-target candidate: **risdiplam** → MTNR1A (iPTM=0.892)
  mechanismconf 89%
• Off-target candidate: **fasudil** → MTNR1A (iPTM=0.877)
  mechanismconf 88%
• Off-target candidate: **risdiplam** → MTNR1A (iPTM=0.867)
  mechanismconf 87%
• Off-target candidate: **riluzole** → MTNR1A (iPTM=0.858)
  mechanismconf 86%
• Off-target candidate: **4AP_ampyra** → MTNR1A (iPTM=0.814)
  mechanismconf 81%

Top compound hits (0)

No ranked compounds yet for MTNR1A.

Linked claims (0)

No claims linked.