Linked hypotheses (20)

• Cross-segment PPI: PERP_ECL1 × KCNA2_pore (iPTM=0.910)
  mechanismconf 91%
• Predicted PPI: PERP_ECL1 × KCNA2_pore (iPTM=0.910)
  mechanismconf 91%
• KCNA2 × PERP interaction (auto-validated BOLTZ2_PPI iPTM=0.91)
  mechanismconf 91%
• Y27632 binds KCNA2_pore (Boltz-2 iPTM=0.886)
  targetconf 89%
• Y27632 × KCNA2_pore affinity via computational screening (Boltz-2)
  mechanismconf 89%
• LIMKi3 × KCNA2_pore affinity via computational screening (Boltz-2)
  mechanismconf 88%
• LIMKi3 binds KCNA2_pore (Boltz-2 iPTM=0.881)
  targetconf 88%
• Predicted PPI: PERP_ECL1 × KCNA2_pore (iPTM=0.881)
  mechanismconf 88%
• Cross-segment PPI: PERP_ECL1 × KCNA2_pore (iPTM=0.881)
  mechanismconf 88%
• 4AP × KCNA2_pore affinity via computational screening (Boltz-2)
  mechanismconf 87%
• 4AP binds KCNA2_pore (Boltz-2 iPTM=0.868)
  targetconf 87%
• MN25_ROCK2 × KCNA2_pore affinity via computational screening (Boltz-2)
  mechanismconf 87%
• MN25_ROCK2 binds KCNA2_pore (Boltz-2 iPTM=0.865)
  targetconf 87%
• BDNF_mimic × KCNA2_pore affinity via computational screening (Boltz-2)
  mechanismconf 87%
• BDNF_mimic binds KCNA2_pore (Boltz-2 iPTM=0.868)
  targetconf 87%
• PAK4_chembl_1 × KCNA2_pore affinity via computational screening (Boltz-2)
  mechanismconf 86%
• PAK4_chembl_1 binds KCNA2_pore (Boltz-2 iPTM=0.864)
  targetconf 86%
• MuSK_chembl_1 binds KCNA2_pore (Boltz-2 iPTM=0.851)
  targetconf 85%
• MuSK_chembl_1 × KCNA2_pore affinity via computational screening (Boltz-2)
  mechanismconf 85%
• Cross-segment PPI: PERP_ECL1 × KCNA2_pore (iPTM=0.835)
  mechanismconf 84%

Top compound hits (0)

No ranked compounds yet for KCNA2.

Linked claims (1)