Linked hypotheses (20)

• ataluren off-target binding to ACVR2B
  repurposingconf 97%
• Off-target candidate: **ataluren** → ACVR2B (iPTM=0.971)
  mechanismconf 97%
• Off-target candidate: **ataluren** → ACVR2B (iPTM=0.972)
  mechanismconf 97%
• Off-target candidate: **ataluren** → ACVR2B (iPTM=0.967)
  mechanismconf 97%
• ataluren off-target binding to ACVR2B
  repurposingconf 95%
• Off-target candidate: **4AP_ampyra** → ACVR2B (iPTM=0.906)
  mechanismconf 91%
• Off-target candidate: **4AP_ampyra** → ACVR2B (iPTM=0.897)
  mechanismconf 90%
• Off-target candidate: **fasudil** → ACVR2B (iPTM=0.894)
  mechanismconf 89%
• Off-target candidate: **fasudil** → ACVR2B (iPTM=0.867)
  mechanismconf 87%
• Off-target candidate: **fasudil** → ACVR2B (iPTM=0.873)
  mechanismconf 87%
• Off-target candidate: **fasudil** → ACVR2B (iPTM=0.860)
  mechanismconf 86%
• Off-target candidate: **4AP_ampyra** → ACVR2B (iPTM=0.844)
  mechanismconf 84%
• Off-target candidate: **4AP_ampyra** → ACVR2B (iPTM=0.822)
  mechanismconf 82%
• Off-target candidate: **risdiplam** → ACVR2B (iPTM=0.809)
  mechanismconf 81%
• Off-target candidate: **riluzole** → ACVR2B (iPTM=0.790)
  mechanismconf 79%
• riluzole off-target binding to ACVR2B
  repurposingconf 79%
• Off-target candidate: **riluzole** → ACVR2B (iPTM=0.792)
  mechanismconf 79%
• Off-target candidate: **riluzole** → ACVR2B (iPTM=0.791)
  mechanismconf 79%
• risdiplam off-target binding to ACVR2B
  repurposingconf 78%
• Off-target candidate: **risdiplam** → ACVR2B (iPTM=0.784)
  mechanismconf 78%

Top compound hits (0)

No ranked compounds yet for ACVR2B.

Linked claims (40)