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SMA Research Platform

Evidence graph for Spinal Muscular Atrophy

Biology-first target discovery
Christian Fischer / Bryzant Labs
—Targets
—Trials
—Drugs
—Datasets
—Sources
—Claims
—Evidence
—Hypotheses

Cross-Paper Synthesis

6 analysis streams

Non-obvious connections across thousands of curated claims from different papers — the platform’s core differentiator. The synthesis engine builds a co-occurrence matrix across all claims, identifies statistically significant target pairs, and generates synthesis cards that explain the biological connection with full citation trails.

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