AF3 Structure Predictions
COMPUTATIONALLIVEAlphaFold-3 computational structure predictions. Tier names are viewing bins: Top ≥0.85, Strong 0.70–0.85, Borderline 0.50–0.70, Weak <0.50 iPTM. They do not establish affinity, experimental success or suitability of a target construct. Header totals cover all axes; the result count below reflects the selected filters.
How to interpret AF3 scores
ipSAE and interface PAE provide additional structure-level measurements. The optional combined-threshold filter selects iPTM ≥0.80, ipSAE_max ≥0.70 and ipSAE_min ≥0.60. These cutoffs are not universal inclusion or readiness criteria. Missing measurements are not failed experiments. Interpret scores alongside exact identities, constructs, raw artifacts and run-specific evidence.
Interface PAE (column “IF-PAE Å”) comes from AF3's own chain_pair_pae_min and measures how well the relative placement of two chains is defined — here lower is better, the opposite direction to every other column. Unlike ipSAE it also applies to protein–ligand folds, so it covers of this table instead of . Below 2 Å the placement is very well defined; at 10 Å and above it is essentially undefined. It disagrees with iPTM more often than one would expect: measured 2026-08-21, 126 folds scored iPTM ≥ 0.80 at an interface PAE of 5 Å or more.
This table loads one page of liveresults at a time. Use Refresh or enable auto-refresh to check for new folds every 60 s. The scores behind them do not all refresh at that pace: iPTM and pTM come with the fold itself, ipSAE is computed by a job running twice an hour, and interface PAE is collected by a batch job that is currently started by hand. A brand-new fold can therefore appear in this table with a dash in the ipSAE and IF-PAE columns for a while — that is a pending measurement, not a negative result.
Axes are recorded run tags or target-linked catalogue associations, not proof that a complete axis was tested. Counts can overlap. All original score outcomes are included; tier filters are optional.