SMA Research Platform

Evidence graph for Spinal Muscular Atrophy

Biology-first target discovery
Christian Fischer / Bryzant Labs
15,945Targets
453Trials
85Drugs
7Datasets
8,004Sources
221,723Claims
232,882Evidence
73,172Hypotheses

AF3 Structure Predictions

COMPUTATIONALLIVE
0 jobs · 0 top · 0 strong · 0 borderline

AlphaFold-3 predictions cross-validating protein–protein interfaces in the SMA pathology graph. Each job produces up to 5 model seeds; the best by ranking_score is shown. iPTM ≥ 0.85= high-confidence interface, 0.70–0.85 strong, 0.50–0.70 borderline, <0.50 weak/refuted. This table is live— it polls the API every 60 s, so newly-completed folds appear automatically.

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