Target Priority Engine v2
COMPUTATIONALMulti-criteria decision engine integrating 6 data dimensions: evidence convergence (25%), druggability via DiffDock screening (20%), ESM-2 structural uniqueness (15%), clinical validation from drug outcomes (15%), cross-species conservation (10%), and target novelty (15%).
▶How does Priority Engine work?
Tier thresholds: Tier 1 Actionable ≥ 0.60 (ready for drug design), Tier 2 Promising≥ 0.40 (strong candidate, needs validation), Tier 3 Exploratory≥ 0.20 (emerging target), Tier 4 Insufficient< 0.20.
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