SMA Research Platform

Evidence graph for Spinal Muscular Atrophy

Biology-first target discovery

API Docs·GitHub

Christian Fischer / Bryzant Labs

—Targets

—Trials

—Drugs

—Datasets

—Sources

—Claims

—Evidence

—Hypotheses

ML Docking Proxy

COMPUTATIONAL

Machine learning surrogate trained on DiffDock v2.2 results. Uses RDKit Morgan fingerprints (ECFP4, 2048-bit) + RandomForest to predict binding confidence ~1000× faster than physics-based docking. Enables screening millions of molecules on CPU in minutes.

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