SMA Research Platform

Evidence graph for Spinal Muscular Atrophy

Biology-first target discovery
Christian Fischer / Bryzant Labs
14,766Targets
453Trials
84Drugs
7Datasets
6,987Sources
64,683Claims
72,052Evidence
29,649Hypotheses
DRUGpreclinicalsmall molecule

ki-696

Mechanism

Non-covalent KEAP1 Kelch-domain PPI inhibitor, Kd = 1.3 nM. Reference tool compound for pure occupancy-based NRF2 activation (distinguishes from electrophilic triterpenoids).

Related claims (0)

No claims matched “ki-696” in free-text search.

Off-Target Findings (0)

No Boltz-2 / Chai-1 off-target panel claims recorded for this drug.

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