DRUGapprovedsmall molecule
givinostat
Mechanism
HDAC class I + IIb inhibitor. FDA approved 2024-03-21 for Duchenne Muscular Dystrophy (Duvyzat, Italfarmaco). SMA repurposing candidate per Osseni 2026.
Structure
ON=C(/C=C/c1ccc(CN2CCN(Cc3ccc(C(=O)N(C)CC4CCCO4)cc3)CC2)cc1)O
Related claims (0)
No claims matched “givinostat” in free-text search.
Off-Target Findings (0)
No Boltz-2 / Chai-1 off-target panel claims recorded for this drug.