DRUGphase1antibody
adimanebart
Brand names: ARGX-119, adimanebart
Mechanism
First-in-class humanized agonist IgG4 antibody binding MuSK extracellular domain. Activates MuSK → drives AChR clustering and NMJ stabilization. Differs from MG anti-MuSK antagonists.
Related claims (0)
No claims matched “adimanebart” in free-text search.
Off-Target Findings (0)
No Boltz-2 / Chai-1 off-target panel claims recorded for this drug.